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Postconcussional Syndrome

Clinical Diagnosis and Treatment
  • Author Footnotes
    1 Present address: 7200 Cambridge, 9th Floor Houston, TX 77030.
    Ashley A. Taylor
    Footnotes
    1 Present address: 7200 Cambridge, 9th Floor Houston, TX 77030.
    Affiliations
    Department of Psychological, Health, and Learning Sciences, Houston, TX, USA
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  • Author Footnotes
    1 Present address: 7200 Cambridge, 9th Floor Houston, TX 77030.
    Stephen R. McCauley
    Footnotes
    1 Present address: 7200 Cambridge, 9th Floor Houston, TX 77030.
    Affiliations
    Department of Neurology, Baylor College of Medicine, Houston, TX 77030, USA

    H. Ben Taub Department of Physical Medicine & Rehabilitation, Baylor College of Medicine, Houston, TX 77030, USA

    Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
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  • Adriana M. Strutt
    Correspondence
    Corresponding author. UH College of Education, Stephen Power Farish Hall, 3657 Cullen Blvd, Room 491, Houston, TX 77204-5023.
    Affiliations
    Department of Neurology, Baylor College of Medicine, Houston, TX 77030, USA

    Department of Psychiatry & Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA
    Search for articles by this author
  • Author Footnotes
    1 Present address: 7200 Cambridge, 9th Floor Houston, TX 77030.
Published:October 31, 2022DOI:https://doi.org/10.1016/j.ncl.2022.08.003

      Keywords

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      References

        • Menon D.K.
        • Schwab K.
        • Wright D.W.
        • et al.
        Position statement: definition of traumatic brain injury.
        Arch Phys Med Rehabil. 2010; 91: 1637-1640
      1. Traumatic brain injury/concussion. Centers for Disease Control and Prevention.
        (Available at:) (Accessed May 9, 2022)
        • McCrory P.
        • Meeuwisse W.H.
        • Echemendia R.J.
        • et al.
        What is the lowest threshold to make a diagnosis of concussion?.
        Br J Sports Med. 2013; 47: 268-271
        • Mayer A.R.
        • Quinn D.K.
        • Master C.L.
        The spectrum of mild traumatic brain injury.
        Neurology. 2017; 89: 623-632
        • Lefevre-Dognin C.
        • Cogné M.
        • Perdrieau V.
        • et al.
        Definition and epidemiology of mild traumatic brain injury.
        Neurochirurgie. 2021; 67: 218-221
        • Silverberg N.D.
        • Iverson G.L.
        • Arciniegas D.B.
        • et al.
        Expert panel survey to update the American Congress of rehabilitation medicine definition of mild traumatic brain injury.
        Arch Phys Med Rehabil. 2021; 102: 76-86
        • Aminoff M.J.
        • Josephson S.A.
        • Aminoff M.J.
        Aminoff’s Neurology and General Medicine. Fifth Edition. Elsevier Science & Technology, 2014
        • Stucky K.J.
        • Kirkwood M.W.
        • Donders J.
        Clinical neuropsychology study guide and board review.
        Oxford University Press, New York, NY2020
        • Strauss I.
        • Savitsky N.
        THe sequelae of head injury.
        Am J Psychiatry. 1934; 91: 189-202
      2. https://www.acrm.org/wp-content/uploads/pdf/TBIDef_English_10-10.pdf (Accessed June 1, 2022).

        • Boyd W.D.
        Post-concussion syndrome: an evidence based approach.
        Xlibris, United States2014
        • Bazarian J.J.
        • Atabaki S.
        Predicting postconcussion syndrome after minor traumatic brain injury.
        Acad Emerg Med. 2001; 8: 788-795
        • Ryan L.M.
        • Warden D.L.
        Post concussion syndrome.
        Int Rev Psychiatry. 2003; 15: 310-316
        • McCauley S.R.
        • Boake C.
        • Pedroza C.
        • et al.
        Postconcussional disorder: Are the DSM-IV criteria an improvement over the ICD-10?.
        J Nerv Ment Dis. 2005; 193: 540-550
        • Centers for Disease Control and Prevention
        Report to congress: traumatic brain injury in the United States. Centers for Disease Control and Prevention.
        (Available at:) (Accessed April 17, 2022)
        • Boake C.
        • McCauley S.R.
        • Levin H.S.
        • et al.
        Diagnostic criteria for postconcussional syndrome after mild to moderate traumatic brain injury.
        J Neuropsychiatry Clin Neurosci. 2005; 17: 350-356
        • Barlow K.M.
        • Crawford S.
        • Stevenson A.
        • et al.
        Epidemiology of postconcussion syndrome in pediatric mild traumatic brain injury.
        Pediatrics. 2010; 126https://doi.org/10.1542/peds.2009-0925
        • Spinos P.
        • Sakellaropoulos G.
        • Georgiopoulos M.
        • et al.
        Postconcussion syndrome after mild traumatic brain injury in Western Greece.
        J Trauma Inj Infect Crit Care. 2010; 69: 789-794
        • McCauley S.R.
        • Wilde E.A.
        • Miller E.R.
        • et al.
        Comparison of ICD-10 and DSM-IV Criteria for Postconcussion Syndrome/Disorder.
        La Revista Iberoamericana de Neuropsicología. 2018; 1: 63-81
        • Polinder S.
        • Cnossen M.C.
        • Real R.G.
        • et al.
        A multidimensional approach to post-concussion symptoms in mild traumatic brain injury.
        Front Neurol. 2018; 9https://doi.org/10.3389/fneur.2018.01113
        • Balakrishnan B.
        • Rus R.M.
        • Chan K.H.
        • et al.
        Prevalence of postconcussion syndrome after mild traumatic brain injury in young adults from a single neurosurgical center in east coast of malaysia.
        Asian J Neurosurg. 2019; 14: 201-205
        • Boake C.
        • McCauley S.R.
        • Levin H.S.
        • et al.
        Limited agreement between criteria-based diagnoses of postconcussional syndrome.
        J Neuropsychiatry Clin Neurosciences. 2004; 16: 493-499
        • Permenter C.M.
        • Fernández-de Thomas R.J.
        • Sherman Al
        Postconcussive Syndrome.
        in: StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL)2022 (Available at:)
        • Dimberg E.L.
        • Burns T.M.
        Management of common neurologic conditions in sports.
        Clin Sports Med. 2005; 24: 637-662
        • Kutcher J.S.
        • Eckner J.T.
        At-risk populations in sports-related concussion.
        Curr Sports Med Rep. 2010; 9: 16-20
        • McCrory P.
        • Meeuwisse W.
        • Johnston K.
        Consensus statement on concussion in sport: 3rd International Conference on Concussion in Sport held in Zurich, November 2008.
        Clin J Sport Med. 2009; 19: 185-200
        • Paniak C.
        Patient complaints within 1 month of mild traumatic brain injury: a controlled study.
        Arch Clin Neuropsychol. 2002; 17: 319-334
        • Ettenhofer M.L.
        • Reinhardt L.E.
        • Barry D.M.
        Predictors of neurobehavioral symptoms in a university population: a multivariate approach using a postconcussive symptom questionnaire.
        J Int Neuropsychological Soc. 2013; 19: 977-985
        • Meares S.
        • Shores E.A.
        • Taylor A.J.
        • et al.
        Mild traumatic brain injury does not predict acute postconcussion syndrome.
        J Neurol Neurosurg Psychiatry. 2008; 79: 300-306
        • van der Horn H.J.
        • Liemburg E.J.
        • Scheenen M.E.
        • et al.
        Brain network dysregulation, emotion, and complaints after mild traumatic brain injury.
        Hum Brain Mapp. 2016; 37: 1645-1654
        • Ponsford J.
        • Cameron P.
        • Fitzgerald M.
        • et al.
        Predictors of postconcussive symptoms 3 months after mild traumatic brain injury.
        Neuropsychology. 2012; 26: 304-313
        • Lange R.T.
        • Iverson G.L.
        • Rose A.
        Post-concussion symptom reporting and the "good-old-days" bias following mild traumatic brain injury.
        Arch Clin Neuropsychol. 2010; 25: 442-450
        • Voormolen D.C.
        • Cnossen M.C.
        • Spikman J.
        • et al.
        Rating of pre-injury symptoms over time in patients with mild traumatic brain injury: the good-old-days bias revisited.
        Brain Inj. 2020; 34: 1001-1009
        • Brooks B.L.
        • Kadoura B.
        • Turley B.
        • et al.
        Perception of recovery after pediatric mild traumatic brain injury is influenced by the "Good Old Days" bias: tangible implications for clinical practice and outcomes research.
        Arch Clin Neuropsychol. 2013; 29: 186-193
        • McCrea M.A.
        Mild traumatic brain injury and postconcussion syndrome: the new evidence base for diagnosis and treatment.
        Oxford University Press, New York2008
        • Fenton G.
        • McClelland R.
        • Montgomery A.
        • et al.
        The postconcussional syndrome: social antecedents and psychological sequelae.
        Br J Psychiatry. 1993; 162: 493-497
        • Evans R.W.
        The postconcussion syndrome and the sequelae of mild head injury.
        Neurol Clin. 1992; 10: 815-847
        • Zemek R.L.
        • Farion K.J.
        • Sampson M.
        • et al.
        Prognosticators of persistent symptoms following pediatric concussion.
        JAMA Pediatr. 2013; 167: 259
        • Ewing-Cobbs L.
        • Cox Jr., C.S.
        • Clark A.E.
        • et al.
        Persistent postconcussion symptoms after injury.
        Pediatrics. 2018; 142: e20180939
        • Mollayeva T.
        • Shapiro C.M.
        • Cassidy J.D.
        • et al.
        Assessment of concussion/mild traumatic brain injury-related fatigue, alertness, and daytime sleepiness: a diagnostic modelling study.
        Neuropsychiatry. 2017; 07https://doi.org/10.4172/neuropsychiatry.1000184
        • Zakzanis K.K.
        • Yeung E.
        Base rates of post-concussive symptoms in a nonconcussed multicultural sample.
        Arch Clin Neuropsychol. 2011; 26: 461-465
        • Valovich McLeod T.C.
        • Wagner A.J.
        • Bacon C.E.
        Lived experiences of adolescent athletes following sport-related concussion.
        Orthopaedic J Sports Med. 2017; 5 (232596711774503)https://doi.org/10.1177/2325967117745033
        • Kim S.H.
        • Olabarrieta-Landa L.
        • Gilboa-Fried S.
        • et al.
        Factor structure models for the post-concussion syndrome scale with monolingual Spanish-speaking adults from Colombia.
        Brain Inj. 2019; 33: 1436-1441
        • Iverson G.L.
        • Brooks B.L.
        • Ashton V.L.
        • et al.
        Interview versus questionnaire symptom reporting in people with the postconcussion syndrome.
        J Head Trauma Rehabil. 2010; 25: 23-30
        • Sullivan K.
        • Garden N.
        A comparison of the psychometric properties of 4 postconcussion syndrome measures in a nonclinical sample.
        J Head Trauma Rehabil. 2011; 26: 170-176
        • King N.S.
        • Crawford S.
        • Wenden F.J.
        • et al.
        The rivermead post concussion symptoms questionnaire: a measure of symptoms commonly experienced after head injury and its reliability.
        J Neurol. 1995; 242: 587-592
        • Gouvier W.
        Postconcussion symptoms and daily stress in normal and head-injured college populations.
        Arch Clin Neuropsychol. 1992; 7: 193-211
        • Iverson G.L.
        • Page J.L.
        • Koehler B.E.
        • et al.
        Test of memory malingering (TOMM) scores are not affected by chronic pain or depression in patients with fibromyalgia.
        Clin Neuropsychologist. 2007; 21: 532-546
        • Gunstad J.
        • Suhr J.
        Perception of illness: Nonspecificity of postconcussion syndrome symptom expectation.
        J Int Neuropsychological Soc. 2002; 8: 37-47
        • Evans R.W.
        Post-traumatic headaches.
        Neurol Clin. 2004; 22: 237-249
        • McBeath J.G.
        • Nanda A.
        Use of dihydroergotamine in patients with postconcussion syndrome.
        Headache: J Head Face Pain. 1994; 34: 148-151
        • Zhou Y.
        • Greenwald B.D.
        Update on Insomnia after Mild Traumatic Brain Injury.
        Brain Sci. 2018; 8: 223
        • Fann J.R.
        • Uomoto J.M.
        • Katon W.J.
        Sertraline in the treatment of major depression following mild traumatic brain injury.
        J Neuropsychiatry Clin Neurosciences. 2000; 12: 226-232
        • Jorge R.E.
        • Acion L.
        • Burin D.I.
        • et al.
        Sertraline for preventing mood disorders following traumatic brain injury: a randomized clinical trial.
        JAMA Psychiatry. 2016; 73: 1041-1047
        • Fann J.R.
        • Uomoto J.M.
        • Katon W.J.
        Cognitive improvement with treatment of depression following mild traumatic brain injury.
        Psychosomatics. 2001; 42: 48-54
        • Han B.I.
        • Song H.S.
        • Kim J.S.
        Vestibular rehabilitation therapy: Review of indications, mechanisms, and key exercises.
        J Clin Neurol. 2011; 7: 184
        • Alsalaheen B.A.
        • Mucha A.
        • Morris L.O.
        • et al.
        Vestibular rehabilitation for dizziness and balance disorders after concussion.
        J Neurol Phys Ther. 2010; 34: 87-93
        • Twamley E.W.
        • Jak A.J.
        • Delis D.C.
        • et al.
        Cognitive Symptom Management and rehabilitation therapy (cogsmart) for veterans with traumatic brain injury: Pilot randomized controlled trial.
        J Rehabil Res Development. 2014; 51: 59-70
        • Elgmark Andersson E.
        • Emanuelson I.
        • Björklund R.
        • et al.
        Mild traumatic brain injuries: the impact of early intervention on late sequelae. A randomized controlled trial.
        Acta Neurochirurgica. 2007; 149: 151-160
        • Elgmark Andersson E.
        • Kärrdahl Bedics B.
        • Falkmer T.
        Mild traumatic brain injuries: a 10-year follow-up.
        J Rehabil Med. 2011; 43: 323-329
        • Al Sayegh A.
        • Sandford D.
        • Carson A.J.
        Psychological approaches to treatment of Postconcussion Syndrome: a systematic review.
        J Neurol Neurosurg Psychiatry. 2010; 81: 1128-1134
        • Silverberg N.D.
        • Hallam B.J.
        • Rose A.
        • et al.
        Cognitive-behavioral prevention of postconcussion syndrome in at-risk patients.
        J Head Trauma Rehabil. 2013; 28: 313-322
        • Bedard M.
        • Felteau M.
        • Mazmanian D.
        • et al.
        Pilot evaluation of a mindfulness-based intervention to improve quality of life among individuals who sustained traumatic brain injuries.
        Disabil Rehabil. 2003; 25: 722-731
        • Hanna-Pladdy B.
        • Berry Z.M.
        • Bennett T.
        • et al.
        Stress as a diagnostic challenge for postconcussive symptoms: Sequelae of mild traumatic brain injury or physiological stress response.
        Clin Neuropsychologist. 2001; 15: 289-304
        • McMillan T.
        • Robertson I.H.
        • Brock D.
        • et al.
        Brief mindfulness training for attentional problems after traumatic brain injury: a randomised control treatment trial.
        Neuropsychological Rehabil. 2002; 12: 117-125
        • Mittenberg W.
        • Burton D.B.
        A survey of treatments for post-concussion syndrome.
        Brain Inj. 1994; 8: 429-437
        • Mittenberg W.
        • Tremont G.
        • Zielinski R.E.
        • et al.
        Cognitive-behavioral prevention of postconcussion syndrome.
        Arch Clin Neuropsychol. 1996; 11 (PMID 14588914): 139-145
        • Boussi-Gross R.
        • Golan H.
        • Fishlev G.
        • et al.
        Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury - randomized prospective trial.
        PLoS One. 2013; 8https://doi.org/10.1371/journal.pone.0079995
        • Hallett M.
        Transcranial magnetic stimulation and the human brain.
        Nature. 2000; 406: 147-150
        • Kobayashi M.
        • Pascual-Leone A.
        Transcranial magnetic stimulation in neurology.
        Lancet Neurol. 2003; 2: 145-156
        • Koski L.
        • Kolivakis T.
        • Yu C.
        • et al.
        Noninvasive brain stimulation for persistent postconcussion symptoms in mild traumatic brain injury.
        J Neurotrauma. 2015; 32: 38-44
        • Triebel K.L.
        • Martin R.C.
        • Novack T.A.
        • et al.
        Treatment consent capacity in patients with traumatic brain injury across a range of injury severity.
        Neurology. 2012; 78: 1472-1478
        • Iverson G.L.
        Outcome from mild traumatic brain injury.
        Curr Opin Psychiatry. 2005; 18: 301-317
        • Alexander M.P.
        Mild traumatic brain injury: pathophysiology, natural history, and Clinical Management.
        Neurology. 1995; 45: 1253-1260
        • Rutherford W.H.
        • Merrett J.D.
        • McDonald J.R.
        Symptoms at one year following concussion from minor head injuries.
        Injury. 1979; 10: 225-230